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Amifostine
Chemical name: Amifostine
 
 
Molecular formula: C5H15N2O3PS
 
Molecular weight: 214.224
 
Chemical structure:
 
                                         
CAS.No: 20573-88-6
 
Standard: USP 34
 
Assay: 99.0%
 
Characters: white or slight yellow crystalline powder.
 
Package: 25kg fiber drum
 
Storage: Stored in a well-closed container, protected from light.
 
Function: Amifostine is used therapeutically to reduce the incidence of neutropenia-related fever and infection induced by DNA-binding chemotherapeutic agents including alkylating agents (e.g. cyclophosphamide) and platinum-containing agents (e.g. cisplatin). It is also used to decrease the cumulative nephrotoxicity associated with platinum-containing agents. Amifostine is also indicated to reduce the incidence of xerostomia in patients undergoing radiotherapy for head and neck cancer.
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